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Becker, J.B. 2013. Pair housing differentially influences motivation to self-administer cocaine in male and woman rats.
In rodents, estradiol in female rats enhances acquisition and escalation of drug having, commitment for medications of abuse, and relapse-like behaviors. These benefits propose that estradiol is critical for the initiation of drug taking, but the moment the conduct is well founded, it is no more time beneath ovarian hormone regulation. But as soon as the addictive habits is proven, the hormones do not continue to play as vital a function in rats or humans.
For illustration, if a mom rat undergoes restraint anxiety for the duration of the previous 7 days of gestation, the period of time when the fetal testes are ordinarily masculinizing the mind, there are permanent effects on mind and conduct (Kerchner and Ward 1992 de Souza et al.
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